Influenza poses a serious risk to adults aged 65 and older. This age group faces higher chances of severe flu complications, hospitalizations, and fatalities due to weaker immune systems. The CDC and ACIP recommend specific flu vaccines to reduce these risks for better protection.

Preferred Flu Vaccines for Seniors

1. High-Dose Inactivated Flu Vaccine (Fluzone High-Dose)
   • It contains four times more antigens than standard-dose vaccines.
   • Offers stronger immune responses and better protection.
   • Studies show it reduces flu-related hospitalizations significantly.
2. Recombinant Flu Vaccine (Flublok Quadrivalent)
   • Made using recombinant DNA technology, avoiding egg use.
   • Ideal for those with severe egg allergies.
   • Provides a more robust immune response compared to standard-dose vaccines.
3. Adjuvanted Inactivated Flu Vaccine (Fluad Quadrivalent)
   • Includes MF59 adjuvant to boost the immune response.
   • Helps overcome weaker immunity in older adults.
   • Studies suggest it reduces hospitalizations more effectively.

Why These Vaccines Are Better

Older adults have weaker immune systems, so standard vaccines may not work well. High-dose and adjuvanted vaccines are tailored to improve immune responses. These vaccines:

• Increase antibody production.
• Offer stronger protection against severe complications.
• Lower risks of flu-related hospitalizations.

What If Preferred Vaccines Aren’t Available?

If these recommended vaccines are not available, the CDC and ACIP recommends that standard-dose inactivated flu vaccines should still be used. While they may not provide the same level of protection, they’re much better than skipping vaccination.

Vaccines to Avoid

The nasal spray flu vaccine (FluMist) isn’t recommended for those 65 and older. It’s less effective for this age group due to their weaker immune response.

Other Approved Options

Other quadrivalent inactivated flu vaccines are also safe for seniors. These vaccines protect against four flu strains and are suitable alternatives when preferred vaccines aren’t an option.

Importance of Vaccination

Older adults account for most flu-related hospitalizations and deaths. Vaccination is the best way to lower these risks. High-dose and adjuvanted vaccines offer the strongest protection, but any flu shot is better than none. Acting early ensures timely protection against the flu.